BIO-CAT Microbials Publishes Successful Clinical For Their Next Generation Probiotic, Opti-Biome® MB40





BIO-CAT Microbials is excited to announce our peer reviewed publication in coming days, in the Journal of Alternative Therapies in Health and Medicine on our proprietary probiotic strain Opti-Biome® Bacillus subtilis MB40.  The publication titled A randomized, double-blind, placebo-controlled, parallel study evaluating the efficacy of Bacillus subtilis MB40 to reduce abdominal discomfort, gas, and bloating reviews our recent clinical trial on gas and bloating.  The study showed improvement on both gas and bloating scores from the test subjects and notably, was more effective in the male subpopulation.

The purpose for this study was to investigate the affect on probiotic supplementation on gas and bloating in a healthy population.  The study observed 100 healthy subjects using probiotic supplementation over a 4-week period in a double-blind, placebo-controlled, parallel arm approach.  The results demonstrated clinically significant reduction in Gastrointestinal Symptoms Rating Scale score and Abdominal Discomfort, Gas, and Bloating score in the male MB40 group.  Furthermore, the male sub-group demonstrated a 10% improvement in general health score.  These results indicate that Opti-Biome® Bacillus subtilis MB40 may reduce the severity, duration and incidence of gas and bloating.


Opti-Biome® Bacillus subtilis MB40 is a safe, non-GMO, clinically tested, extremely stable, well researched probiotic strain ready to be formulated in dietary supplements or food for all your gas and bloating claims.  Its’ superior stability can help guarantee CFU counts in products that are challenged to meet end of shelf-life claims, generally those that are utilizing lactobacillus and Bifidobacterium species.  MB40 can be a stand-alone probiotic product or custom formulated with our scientifically backed enzyme blends to meet your label requirements.

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Safety Assessment of Bacillus subtilis MB40 for Probiotic Use in Food and Dietary Supplements

Click Here to View or Download BIO-CAT Microbials’ MB40 Manuscript