Why Bacillus?

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New Product Ingredient

Living

Probiotics, as defined by the World Health Organization (WHO), are live microorganisms which when administered in adequate amounts confer a health benefit on the host. These microorganisms have been studied for over 100 years for their effect on overall health and longevity of life.1 Isolation of lactic acid producing species e.g. Lactobacillus spp. and Bifidobacterium spp. have led to dietary supplements and mostly dairy-based consumer products that generally require refrigeration and careful handling to preserve the living microorganisms. While most consumers now understand the potential benefits of “good bacteria” they continue to struggle with how to choose products with living microorganisms. Most dietary supplements are marketed on store shelves without refrigeration, and pasteurization and other processes render traditional probiotic organisms inactive in most food products!

OPTI-BIOME™ Bacillus subtilis MB40 has a natural protective coating that stabilizes them and keeps them alive but in a dormant state until they are ingested.

Rediscovering the Microbiome

Exploration of the human microbiome continues as its diversity, complexity and effect on human health is slowly being understood. These beneficial microorganisms have been recognized to support digestive, neurological, and immune health with more areas under investigation.2  The recently announced NIH Human Microbiome Project promises to provide the link to understanding how these microorganisms may work in improving health and wellness. Bacillus spp. have been isolated from the human intestinal tract.3 They are known to produce a wide variety of digestive enzymes and anti-microbial compounds. They are compatible with and supportive of many other beneficial microorganisms such as Lactobacillus spp., Bifidobacterium spp. and other spore forming species e.g. Bacillus coagulans.4

OPTI-BIOME™ Bacillus subtilis MB40 is a unique probiotic strain that adds compatible diversity to any probiotic formulation.

Stability

Whether you are a manufacturer or consumer of probiotics, shelf-life is important. Ordering, blending, packaging, shipping and stocking takes time. If you are making traditional probiotics, refrigeration is necessary but not always guaranteed during this process that could take weeks if not months. Manufacturers are held accountable for their labeling, and living, active microorganisms may be reduced during this period. As a consumer purchasing these products in the store, questions remain as to whether they actually contain the live microorganisms claimed on their labels.

OPTI-BIOME™ Bacillus subtilis MB40 as manufactured has a natural protective coating that stabilizes them, and keeps them in a living, but dormant state until they are ingested.5 Therefore, living beneficial microorganisms persist without refrigeration.  This stability ensures viability when measured at the end of product shelf life.

USA Manufactured

OPTI-BIOME™ Bacillus subtilis MB40 is produced in Shakopee, MN USA by BIO-CAT Microbials, LLC a manufacturer of Bacillus spp. for over 10 years.  BIO-CAT Microbials operates a high tech, GMP certified facility supported by highly skilled operators and an expert bacterial fermentation technical team.

OPTI-BIOME™ Bacillus subtilis MB40 can be incorporated in Dietary Supplements and Food, Beverage & Ingredients. For more information, please contact us today.

 

References

  1. Metchinikoff, E., Prolongation of Life, William Heinermann, London 1910
  2. Porokulova, I. 2013. Modern status and perspectives of Bacillus bacteria as probiotics. Prob. Health. 1(4):1-5.
  3. Human Microbiome Project NIH July 5, 2016 http://www.hmpdacc.org/catalog/grid.php?dataset=genomic&hmp_isolation_body_site=gastrointestinal_tract
  4. Naruse, et. al. (1978). US Patent Publication 4, 110, 477 A. Washington DC: US Patent and Trademark Office
  5. Gill et al. 2006. Metagenomic Analysis of Human Distal Gut Microbiome Sciece. 312(5778): 1355-1359